The nasal cleaner can hold up well in the dishwasher without melting or deforming the plastic. But we recommend hand wash, it's more hygienic. This Neti wash features a wide mouth that makes it easy to prepare the saline solution. The angled nozzle is an added benefit. You don't need to tilt your head as much as you do with the alternative nose wash bottle. Please do not rinse with plain water which will result in a severe burning sensation. Nasal irrigation up to the fill line with lukewarm distilled water or previously boiled water. Add a packet of nasal wash salt pours into the water. Shake the nose cleaner gently to dissolve the mixture.